Mazdutide Acetate | Product Description
Mazdutide Acetate | Introduction
Mazdutide (IBI362; LY3305677) is a research-use-only, long-acting polypeptide analog of oxyntomodulin that engages both GLP-1 and glucagon receptors in preclinical models of energy balance and metabolic regulation. Investigators use mazdutide to probe bioenergetic adaptation, lipid and glucose handling, and hepatometabolic signaling under caloric or exercise stress. This compound is for controlled laboratory environments only and is not approved for diagnostic or therapeutic use.
- Dual GLP-1/GCG receptor engagement (OXM-analog)
- Supports metabolic flexibility investigations
- Explores energy balance and substrate utilization
Lab Tests
Latest Certificate of Analysis.
Mazdutide Acetate | Molecular Identity & Composition
| Name | Mazdutide Acetate (IBI362; LY3305677) |
| Synonyms | IBI362; LY3305677; OXM-analog dual GLP-1/GCG agonist |
| Sequence | Proprietary OXM-analog sequence (public sources do not disclose full residues) |
| Molecular Formula | C210H322N46O67 |
| Molecular Weight | 4563.14 g/mol |
| CAS Number | 2259884-03-0 |
| Appearance | White to off-white lyophilized powder |
| Solubility | Soluble in sterile water or bacteriostatic water |
| Purity | ≥99% (HPLC) |
| Storage Guidelines | • Before Reconstitution (Lyophilized): Store at or below 0°F (–18°C). Protect from light and moisture. • After Reconstitution (Liquid): Store between 36–46°F (2–8°C). Use promptly; avoid repeated freeze-thaw cycles. • Long-Term Stability: Keep dry and frozen until ready for use. |
LuvionBio Quality Advantage
- ≥99% purity | HPLC & MS validated
- Endotoxin <0.05 EU/mg | Third-party verified
- Controlled nucleation lyophilization | Stability-focused processes
- PhD-formulated | GMP / ISO-aligned manufacturing
- Shipped in Luxe Fridge-Ready Box
Category Overview | Bioenergetic Pathway Modulators
Bioenergetic peptides are used in RUO studies to explore how cells generate, manage, and recover energy. These compounds interact with key metabolic pathways—especially mitochondrial ATP output and redox signaling—supporting research into energy dysfunction, oxidative stress, and stress-resilience under caloric or exercise challenges.
Mazdutide Acetate | Exciting Areas of Study
- Energy balance and substrate utilization in vitro
- Glucose and lipid handling under metabolic stress
- Hepatometabolic signaling in preclinical systems
- Adiposity and thermogenic pathway exploration
- GLP-1/GCG receptor crosstalk dynamics
Mazdutide Acetate | Research Modeling & Applications
- Assess dual-agonist effects on AMPK/PKA-linked readouts
- Profile mitochondrial efficiency and redox balance
- Interrogate insulin sensitivity and nutrient partitioning
- Explore dose-response curves in metabolic cell systems
Research Use Disclaimer
This product is intended solely for laboratory research purposes. It is not suitable for human, animal, or household use. Researchers must follow institutional safety protocols. See our Terms & Conditions and our Research Compliance Disclaimers for details.

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