PE22-28
PE22-28
Research-use-only short peptide studied for signal transduction, receptor engagement, and stress-response transcription in vitro models.
- Probes messaging pathway activation and bias.
- Supports kinetics and transcriptional profiling assays.
- ≥99% Pure | 5X Tested | PhD-Formulated | GMP/ISO
$74.99
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*Disclaimer:
This product is intended solely for laboratory research purposes. It is not suitable for consumption by humans, nor for medical, veterinary, or household purposes.
Researchers should handle Agomelatine with care and adhere to strict safety guidelines during experiments. Kindly review our Terms & Conditions before making a
purchase.
PE22-28 | Product Description
PE22-28 | Introduction
PE22-28 is a heptapeptide fragment studied in RUO signal-transduction models for its ability to interrogate GPCR/ion-channel-linked pathways and downstream transcriptional signatures. It is frequently used to explore TREK-1 pathway modulation and related cellular responses in vitro. Not intended for diagnostic or therapeutic use.
- Ion-channel–linked signaling kinetics
- Pathway bias and downstream transcription
- Comparative profiling vs. parent fragments
PE22-28 | Molecular Identity & Composition
| Name | PE22-28 |
| Synonyms | PE 22-28; GVSWGLR; Spadin (22–28) fragment |
| Sequence | Gly-Val-Ser-Trp-Gly-Leu-Arg (GVSWGLR) |
| Molecular Formula | C35H55N11O9 |
| Molecular Weight | 773.9 g/mol |
| CAS Number | 1801959-12-5 |
| Appearance | White to off-white lyophilized powder |
| Solubility | Soluble in sterile or bacteriostatic water |
| Purity | ≥99% (HPLC), lot-specific |
| Storage Guidelines | • Lyophilized: ≤0°F (–18°C), dry, protected from light/moisture • Reconstituted: 36–46°F (2–8°C); aliquot; avoid repeated freeze–thaw • Long-Term: Store dry at ≤−20°C; desiccated |
LuvionBio Quality Advantage
- Purity & Identity: ≥99% | HPLC & MS validated
- Endotoxin & Sterility: <0.05 EU/mg | Third-party verified
- Stability & Process: Controlled-nucleation lyophilization | Stability-focused procedures
- Formulation & QA: PhD-formulated | GMP / ISO-aligned manufacturing
- Packaging: Luxe Fridge-Ready Box
Category Overview | Signal Transduction Pathways
Signal transduction peptides are used in RUO studies to explore how cells send and receive messages. These signals help control how cells grow, repair themselves, and respond to stress. Researchers use these peptides in lab models to better understand how communication inside cells works—and what happens when it doesn’t.
Exciting Areas of Study
- How cellular signals initiate chain reactions in lab models.
- Peptide effects on messaging pathways like MAPK & PI3K.
- How cells respond to stress in lab models.
- Model disrupted signaling seen in pre-clinical disease research.
Research Applications
- Map how cell signals change under different conditions
- Test how peptides influence key response pathways
- Study how signaling balance affects cell behavior over time
PE22-28 | Research Modeling & Applications
- Interrogate ion-channel–linked signaling (e.g., TREK-1 models)
- Evaluate pathway bias and downstream transcriptional outputs
- Benchmark responses vs. parent fragment analogs
Research Use Disclaimer
This product is intended solely for laboratory research purposes and is not suitable for human, animal, or household use. Researchers must follow institutional safety protocols. See our Terms & Conditions and Research Compliance Disclaimers for details.
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