Tesamorelin Acetate | Product Description
Tesamorelin Acetate | Introduction
Tesamorelin Acetate is an N-terminally modified GHRH(1-44) analog used in RUO signal-transduction models to interrogate GPCR-driven cAMP/PKA signaling and CREB-linked transcription. Studies often quantify receptor engagement, second messengers, and downstream gene expression. Not intended for diagnostic or therapeutic use.
- GHRH-R coupling and cAMP kinetics
- PKA/CREB pathway transcriptional readouts
- Comparisons vs. native GHRH and shorter analogs
Tesamorelin Acetate | Molecular Identity & Composition
| Name | Tesamorelin Acetate |
| Synonyms | Tesamorelin; Egrifta; t-3-Hexenoyl-GHRH(1-44)-NH2 |
| Sequence | t-3-Hexenoyl-Tyr-Ala-Asp-Ala-Ile-Phe-Thr-Asn-Ser-Tyr-Arg-Lys-Val-Leu-Gly-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Met-Ser-Arg-Gln-Gln-Gly-Glu-Ser-Asn-Gln-Glu-Arg-Gly-Ala-Arg-Ala-Arg-Leu-NH2 |
| Molecular Formula | C221H366N72O67S (free base) |
| Molecular Weight | ~5135.8 g/mol (free base) |
| CAS Number | 218949-48-5 (base) |
| Appearance | White to off-white lyophilized powder |
| Solubility | Soluble in sterile or bacteriostatic water |
| Purity | ≥99% (HPLC), lot-specific |
| Storage Guidelines | • Lyophilized: ≤0°F (–18°C), dry, protected from light/moisture • Reconstituted: 36–46°F (2–8°C); short-term only • Long-Term: Store dry at ≤−20°C; avoid freeze–thaw |
LuvionBio Quality Advantage
- Purity & Identity: ≥99% | HPLC & MS validated
- Endotoxin & Sterility: <0.05 EU/mg | Third-party verified
- Stability & Process: Controlled-nucleation lyophilization | Stability-focused procedures
- Formulation & QA: PhD-formulated | GMP / ISO-aligned manufacturing
- Packaging: Luxe Fridge-Ready Box
Category Overview | Signal Transduction Pathways
Signal transduction peptides are used in RUO studies to explore how cells send and receive messages. These signals help control how cells grow, repair themselves, and respond to stress. Researchers use these peptides in lab models to better understand how communication inside cells works—and what happens when it doesn’t.
Exciting Areas of Study
- How cellular signals initiate chain reactions in lab models.
- Peptide effects on messaging pathways like MAPK & PI3K.
- How cells respond to stress in lab models.
- Model disrupted signaling seen in pre-clinical disease research.
Research Applications
- Map how cell signals change under different conditions
- Test how peptides influence key response pathways
- Study how signaling balance affects cell behavior over time
Tesamorelin Acetate | Research Modeling & Applications
- Quantify GHRH-R–cAMP–PKA–CREB signaling chains
- Benchmark transcriptional programs vs. GHRH(1-44)
- Profile bias/kinetics across receptor contexts
Research Use Disclaimer
This product is intended solely for laboratory research purposes and is not suitable for human, animal, or household use. Researchers must follow institutional safety protocols. See our Terms & Conditions and Research Compliance Disclaimers for details.

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