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VIP

VIP

Research-use-only 28-mer neuropeptide studied for VPAC1/VPAC2 receptor signaling, cAMP/PKA pathways, and transcriptional responses.

  • Probes GPCR coupling and pathway bias.
  • Supports second-messenger and gene assays.
  • ≥99% Pure | 5X Tested | PhD-Formulated | GMP/ISO

Price range: $44.99 through $74.99

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*Disclaimer:
This product is intended solely for laboratory research purposes. It is not suitable for consumption by humans, nor for medical, veterinary, or household purposes.
Researchers should handle Agomelatine with care and adhere to strict safety guidelines during experiments. Kindly review our Terms & Conditions before making a
purchase.

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VIP (Vasoactive Intestinal Peptide) | Product Description

VIP | Introduction

VIP is a 28-amino-acid neuropeptide used in RUO models to study GPCR-mediated signal transduction via VPAC1/VPAC2 and downstream cAMP/PKA/CREB responses. Typical assays include receptor selectivity, second-messenger kinetics, and transcriptional mapping. Not intended for diagnostic or therapeutic use.

  • VPAC1/VPAC2 engagement and bias profiling
  • cAMP/PKA–linked transcriptional outputs
  • Signal timing/kinetics under stress paradigms

VIP | Molecular Identity & Composition

Name Vasoactive Intestinal Peptide (VIP)
Synonyms VIP; Vasoactive Intestinal Polypeptide
Sequence His-Ser-Asp-Ala-Val-Phe-Thr-Asp-Asn-Tyr-Thr-Arg-Leu-Arg-Lys-Gln-Met-Ala-Val-Lys-Lys-Tyr-Leu-Asn-Ser-Ile-Leu-Asn-NH2
Molecular Formula C147H237N43O43S
Molecular Weight ~3326.8 g/mol
CAS Number 40077-57-4 (human VIP)
Appearance White to off-white lyophilized powder
Solubility Soluble in sterile or bacteriostatic water
Purity ≥99% (HPLC), lot-specific
Storage Guidelines Lyophilized: ≤0°F (–18°C), dry, protected from light/moisture
Reconstituted: 36–46°F (2–8°C); short-term only
Long-Term: Store dry at ≤−20°C; avoid freeze–thaw

LuvionBio Quality Advantage

  • Purity & Identity: ≥99%  |  HPLC & MS validated
  • Endotoxin & Sterility: <0.05 EU/mg  |  Third-party verified
  • Stability & Process: Controlled-nucleation lyophilization  |  Stability-focused procedures
  • Formulation & QA: PhD-formulated  |  GMP / ISO-aligned manufacturing
  • Packaging: Luxe Fridge-Ready Box

Category Overview  |  Signal Transduction Pathways

Signal transduction peptides are used in RUO studies to explore how cells send and receive messages. These signals help control how cells grow, repair themselves, and respond to stress. Researchers use these peptides in lab models to better understand how communication inside cells works—and what happens when it doesn’t.

Exciting Areas of Study

  • How cellular signals initiate chain reactions in lab models.
  • Peptide effects on messaging pathways like MAPK & PI3K.
  • How cells respond to stress in lab models.
  • Model disrupted signaling seen in pre-clinical disease research.

Research Applications

  • Map how cell signals change under different conditions
  • Test how peptides influence key response pathways
  • Study how signaling balance affects cell behavior over time

VIP  |  Research Modeling & Applications

  • Profile VPAC1/VPAC2 coupling and bias
  • Quantify cAMP–PKA–CREB cascade dynamics
  • Benchmark transcriptional signatures vs. agonist controls

Research Use Disclaimer

This product is intended solely for laboratory research purposes and is not suitable for human, animal, or household use. Researchers must follow institutional safety protocols. See our Terms & Conditions and Research Compliance Disclaimers for details.

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