VIP (Vasoactive Intestinal Peptide) | Product Description
VIP | Introduction
VIP is a 28-amino-acid neuropeptide used in RUO models to study GPCR-mediated signal transduction via VPAC1/VPAC2 and downstream cAMP/PKA/CREB responses. Typical assays include receptor selectivity, second-messenger kinetics, and transcriptional mapping. Not intended for diagnostic or therapeutic use.
- VPAC1/VPAC2 engagement and bias profiling
- cAMP/PKA–linked transcriptional outputs
- Signal timing/kinetics under stress paradigms
VIP | Molecular Identity & Composition
| Name | Vasoactive Intestinal Peptide (VIP) |
| Synonyms | VIP; Vasoactive Intestinal Polypeptide |
| Sequence | His-Ser-Asp-Ala-Val-Phe-Thr-Asp-Asn-Tyr-Thr-Arg-Leu-Arg-Lys-Gln-Met-Ala-Val-Lys-Lys-Tyr-Leu-Asn-Ser-Ile-Leu-Asn-NH2 |
| Molecular Formula | C147H237N43O43S |
| Molecular Weight | ~3326.8 g/mol |
| CAS Number | 40077-57-4 (human VIP) |
| Appearance | White to off-white lyophilized powder |
| Solubility | Soluble in sterile or bacteriostatic water |
| Purity | ≥99% (HPLC), lot-specific |
| Storage Guidelines | • Lyophilized: ≤0°F (–18°C), dry, protected from light/moisture • Reconstituted: 36–46°F (2–8°C); short-term only • Long-Term: Store dry at ≤−20°C; avoid freeze–thaw |
LuvionBio Quality Advantage
- Purity & Identity: ≥99% | HPLC & MS validated
- Endotoxin & Sterility: <0.05 EU/mg | Third-party verified
- Stability & Process: Controlled-nucleation lyophilization | Stability-focused procedures
- Formulation & QA: PhD-formulated | GMP / ISO-aligned manufacturing
- Packaging: Luxe Fridge-Ready Box
Category Overview | Signal Transduction Pathways
Signal transduction peptides are used in RUO studies to explore how cells send and receive messages. These signals help control how cells grow, repair themselves, and respond to stress. Researchers use these peptides in lab models to better understand how communication inside cells works—and what happens when it doesn’t.
Exciting Areas of Study
- How cellular signals initiate chain reactions in lab models.
- Peptide effects on messaging pathways like MAPK & PI3K.
- How cells respond to stress in lab models.
- Model disrupted signaling seen in pre-clinical disease research.
Research Applications
- Map how cell signals change under different conditions
- Test how peptides influence key response pathways
- Study how signaling balance affects cell behavior over time
VIP | Research Modeling & Applications
- Profile VPAC1/VPAC2 coupling and bias
- Quantify cAMP–PKA–CREB cascade dynamics
- Benchmark transcriptional signatures vs. agonist controls
Research Use Disclaimer
This product is intended solely for laboratory research purposes and is not suitable for human, animal, or household use. Researchers must follow institutional safety protocols. See our Terms & Conditions and Research Compliance Disclaimers for details.

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